Centrum vs One A Day: Men’s, Women’s and 50+ Formulas Compared Label by Label

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Centrum and One A Day each sell a men's, a women's and two 50+ tablets, so the lines look like matched pairs; on the panels, they are not. We have no ties to Haleon or Bayer, the distributors named on these labels. We pinned eight labels by their ID in the NIH Dietary Supplement Label Database, read Haleon's own Centrum PDFs and searched the NSF, USP and Informed registries on October 29, 2026. This page is label-checked, not lab-tested: every number is what the panel prints for one tablet.

Before you decide

This is a label comparison for adults choosing between two drugstore multivitamins. It is not medical advice, and it cannot tell you which tablet suits you; that depends on your diet, your bloodwork and your medications. If you are pregnant or shopping for a child, this is the wrong page. Both brands sell separate prenatal products, and our Nature Made vs One A Day prenatal comparison covers that shelf.

Both brands print a caution on the bottle, and the wording is worth reading before any of our tables. The One A Day Men's Complete label in the NIH label database (DSLD 337439) says: "If pregnant, breast-feeding, taking medication, or have any medical condition ask a health professional before use." Haleon's 2025 Centrum Men label PDF says: "If you are taking medications or supplements, and/or have medical conditions, talk to your healthcare provider before use." Read those two lines as the first row of the comparison.

Both brands' labels also carry benefit claims. We did not evaluate them and we do not repeat them here; nothing on this page is a claim about what either tablet does in the body. If you are still deciding whether a daily multi makes sense at all, start with our complete guide to multivitamins and our skeptic's look at whether multivitamins are a waste of money. This page assumes you have narrowed it to these two brands and want to know what differs on the label.

Who makes Centrum and One A Day

Centrum's six 2025 label PDFs on Haleon's label site, files last modified in November 2025, all read "Distributed by: Haleon, Warren, NJ 07059". Older Centrum labels in the NIH database name other companies. The 2021 entries for Centrum Adults and Centrum Women say "Marketed by: Pfizer, Madison, NJ" with 2019 and 2020 copyright lines, and the entries made in 2022 and 2024 say "Distributed by: GSK Consumer Healthcare" or "Dist. by: GSK CH". We are reporting label lines, not corporate history; we did not open any deal documents.

One quirk matters if you look these labels up yourself. On October 29, 2026 a database search for Centrum returned 215 labels under the brand name Centrum, 12 under GSK and none under Haleon, and the Centrum Men and Centrum Silver 50+ labels we used are filed under GSK. A search for the brand "Centrum" alone misses them.

Three of the 2025 Haleon PDFs, for Centrum Men, Silver Men 50+ and Silver Women 50+, print "Made in Canada". The Centrum Women and Centrum Adults PDFs print no country line. NSF's supplement listing places the four Centrum tablets we compared at a facility in Saint Laurent, Québec, under the company name Haleon US Holdings LLC of Warren, NJ.

One A Day is a Bayer line. Its retail labels in the NIH database read "Dist. by: Bayer HealthCare LLC, Whippany, NJ 07981" and "Bayer, the Bayer Cross and One A Day are registered trademarks of Bayer." Two 2020 database entries, for Men's Health Formula and Women's 50+ Healthy Advantage, record "Made in the USA of US & imported materials". We could not confirm a country line on the later One A Day labels. For ownership records on other brands, see our supplement brands hub.

Which labels we compared

For each product we took the label with the latest entry date in the NIH database, said so, and added a second source where one exists: Haleon's own PDF for Centrum, and for One A Day either an older retail label in the same database or the panel image on oneaday.com, which we viewed on October 29, 2026 (an image the brand posts, not a bottle we bought). A later entry date does not always mean newer artwork, as the One A Day rows show, and on two products several entries share the latest date.

We reran the database search for Centrum, GSK and Bayer labels on October 29, 2026 and found no entries newer than the ones above. Centrum Women had seven entries on December 18, 2021; we used 257221, and entries 257055 and 257056 carry the same values. We did not pair Centrum Adults: the newest base adult One A Day tablets in the database, Essential and Maximum, were entered on June 1, 2012, which is too old for a fair match.

One A Day has renamed all four products, and shared UPC codes in the database tie the old and new names to the same lines:

• Men's Health Formula became Men's Complete Multivitamin (UPC 0 16500 08014 5).
• Women's Formula became Women's Complete Multivitamin (UPC 0 16500 07412 0).
• Men's 50+ Healthy Advantage became Men's 50+ Complete Multivitamin (UPC 0 16500 56533 8).
• Women's 50+ Healthy Advantage became Women's 50+ Complete Multivitamin (UPC 0 16500 56531 4).

On October 29, 2026 the product pages on oneaday.com used shorter names, Men's Multi, Women's Multi, Men's 50+ Multi and Women's 50+ Multi, and older product addresses redirected to them. Healthy Advantage, Health Formula, Complete and Multi on a bottle all point to the same four product lines, though not always to the same formula, as the next four sections show.

Men's: Centrum Men vs One A Day Men's Complete

Every number below is copied from the label image in NIH's Dietary Supplement Label Database and, for Centrum, from Haleon's own label PDF, checked October 29, 2026. Percentages are the % Daily Value as printed. "Not listed" means the panel has no row for that nutrient; we write 0 only where the label prints 0.

The clearest difference is iron. Centrum Men lists 8 mg (44% DV); One A Day Men's lists 0 mg (0%), and the retail label entered in February 2023 (DSLD 269984) prints "Does Not Contain Iron". If an iron-free men's tablet is what you are shopping for, only one of these two labels gives you that.

Selenium runs higher on Centrum in this pair, the reverse of the 50+ pair below: 100 mcg (182%) against 55 mcg (100%). Folate is close, 333 mcg DFE against 400, and calcium, zinc and vitamin D are identical. Vitamin K depends on which One A Day label you hold: 30 mcg on the retail label entered in 2023, and no row at all on the 2025 database entry or on the brand's own panel image.

Both brands have listed lycopene, an ingredient with no Daily Value, on this tablet. The 2022 Centrum Men entry lists 600 mcg, Haleon's 2025 PDF lists none, and One A Day Men's lists 300 mcg. That Centrum change is one more reason to read your own panel. For a wider field of men's tablets, see our best multivitamin for men roundup.

Women's: Centrum Women vs One A Day Women's Complete

Both labels list 18 mg iron (100% DV), 8 mg zinc and 25 mcg vitamin D, and their folate figures sit 2 mcg DFE apart on the same 400 mcg of folic acid. The split is in calcium, selenium, B12 and vitamin K. Centrum Women lists 200 mg calcium, 18 mcg selenium and 6 mcg B12; One A Day Women's lists 130 mg, 41 mcg and 9.6 mcg. Centrum lists 50 mcg vitamin K, and the One A Day label we pinned has no K row.

That One A Day label (DSLD 287759) is the new formula tablet its box calls 40% smaller, and the panel image on oneaday.com matched it on October 29, 2026. An earlier classic Women's Complete entry, 270741, which the database flags as off market, listed 400 mg calcium and 25 mcg vitamin K. Same product name, two different panels, so check which one is on your shelf.

The Centrum Women label we used is a 2021 database entry that still names Pfizer as the marketer. Haleon's 2025 PDF for the same tablet prints the same numbers under the Haleon name. In this pair, the Centrum numbers held steady from the Pfizer label to the Haleon PDF. Our best multivitamin for women roundup compares more options in this group.

Men 50+: Centrum Silver Men 50+ vs One A Day Men's 50+

Almost every row differs in this pair. Centrum Silver Men 50+ lists more vitamin D (25 mcg against 17.5 mcg), four times the B12 (100 mcg against 25 mcg), three times the vitamin K (60 mcg against 20 mcg), more calcium (210 mg against 120 mg) and 300 mcg lutein, which One A Day does not list.

One A Day Men's 50+ lists more zinc (24 mg against 15 mg), more than five times the selenium (117 mcg against 21 mcg) and more folate (665 mcg DFE against 500). Neither tablet lists iron.

Vitamin K needs a caveat here. The newest One A Day Men's 50+ entry in the database (DSLD 270560, June 2022) lists 20 mcg, but the panel image on oneaday.com on October 29, 2026 showed no vitamin K row while every other number on it matched. We found no database entry for that version. Read the K row on your own bottle before you rely on our table for it.

Both tablets list lycopene, 600 mcg on Centrum and 370 mcg on One A Day, with no Daily Value for either. The vitamin D gap is easy to miss, because both boxes are 50+ formulas and only one of them lists 25 mcg. Our best multivitamin for men over 50 roundup covers other tablets in this group.

Women 50+: Centrum Silver Women 50+ vs One A Day Women's 50+

These two match on vitamin D (25 mcg) and calcium (300 mg), and their folate is the same 400 mcg of folic acid. Iron is the first split: Centrum Silver Women 50+ lists 8 mg (44% DV), and One A Day Women's 50+ has no iron row. Centrum also lists twice the B12 (50 mcg against 25 mcg), 50 mcg vitamin K and 300 mcg lutein. One A Day lists more zinc (24 mg against 15 mg) and a little more selenium (27 mcg against 22 mcg).

Vitamin K again depends on the label. The 2025 database entry (DSLD 337448) and the oneaday.com panel image show no K row, while the earlier retail label, 270629, lists 20 mcg. Every other number on those two One A Day labels is identical. For the K row, go by the version on your bottle. Our best multivitamin for women over 50 roundup lists more choices in this group.

Where the formulas actually split: iron, vitamin K and lutein

Across the four pairs, vitamin D matches in three, folic acid and calcium match in two each, and the two under 50 pairs list the same zinc. Three rows do most of the separating: iron, vitamin K and lutein.

Lutein on Centrum Silver comes with its own label note: "This product is not intended to provide daily intake of lutein." The Centrum Silver Men 50+ label PDF prints it, and its panel marks the Daily Value for lutein as not established. We list lutein as a label difference and draw no buying advice from it.

The version gaps are the part of this comparison you will not see on the box. One A Day's 2025 database entries for Men's Complete and Women's 50+ Complete are spec sheets with artwork dated February 28 and March 1, 2022, marked "Version 001". Neither lists vitamin K or phylloquinone, even though the Men's sheet says "New Look Same Formula", and the earlier retail labels list 30 mcg and 20 mcg.

One A Day has also sold two Men's and Women's Complete formulas under one name: a classic tablet, and a new formula smaller tablet that lists 130 mg calcium, 41 mcg selenium and no vitamin K.

Centrum has drifted too, on a smaller scale: the 2022 Centrum Men entry lists 600 mcg lycopene, and Haleon's 2025 PDF lists none. The practical rule is the same for both brands. Check the Supplement Facts panel on your bottle against our tables, row by row, and trust the panel where they differ.

The ingredient forms are printed as well, and they mostly match: cyanocobalamin for B12, cholecalciferol for vitamin D, ferrous fumarate for iron where iron appears, and zinc oxide on both. Centrum lists vitamin K as phytonadione and selenium as sodium selenate; One A Day lists phylloquinone and sodium selenite. We draw no conclusion about absorption from those names.

Folate DFE and vitamin D units on these labels

These labels state folate in micrograms of dietary folate equivalents (DFE), with folic acid in parentheses. The definition sits in 21 CFR 101.9: "1 DFE = 1 mcg naturally occurring folate = 0.6 mcg folic acid." So the DFE figure is the folic acid amount divided by 0.6, and every folate number on these eight labels matches that math to within 2 mcg DFE.

The 400 mcg row is the odd one. 400 divided by 0.6 is 666.7; Centrum prints 667 and One A Day prints 665. We could not find a primary source that explains the different rounding, so we show both numbers as printed. Whatever the reason, the folic acid line is identical: 400 mcg on both. To run any label through the same math, use our folate DFE calculator.

The % Daily Value column comes from the same regulation. The Daily Values for adults and children 4 and older are 20 mcg vitamin D, 2.4 mcg B12, 400 mcg DFE folate, 18 mg iron, 1,300 mg calcium, 120 mcg vitamin K, 11 mg zinc and 55 mcg selenium.

Every percentage in our tables equals the amount divided by the Daily Value, rounded to a whole number. For example, 100 mcg of B12 divided by 2.4 mcg gives 4,167%, exactly what Centrum Silver Men 50+ prints. The four digit figure is arithmetic on a small Daily Value; we make no claim about what it means for any one person.

Vitamin D is printed in both units. 25 mcg appears as 1,000 IU on Centrum and as 1000 IU on One A Day, and the One A Day Men's 50+ label prints 17.5 mcg as 700 IU; both work out to 40 IU per microgram. Our vitamin D unit converter does the same conversion for any label.

Third-party listings, checked October 29, 2026

NSF's NSF/ANSI 173 dietary supplement listing for Centrum, timestamped 12:15 a.m. Eastern Time on October 29, 2026, showed 25 Centrum products under Haleon US Holdings LLC. The four Centrum tablets in our comparison were listed under the names Centrum Men Multivitamin, Centrum Women Tablets, Centrum Silver Men 50+ and Centrum Silver Women 50+ Tablets, at the Saint Laurent, Québec facility. The Centrum Adults tablet was not found that day; the listing carried Centrum Adult Liquid and Centrum Adult Multigummies instead.

A listing is tied to a trade name, not to a bottle. NSF's page shows no UPC and no label version, so we cannot say which printing of a Centrum label it covers. We also found no "NSF" text in any of the six Haleon label PDFs, and no NSF mark on the two we viewed as images, Centrum Men and Silver Men 50+.

For One A Day, the same NSF/ANSI 173 search returned "No Matching Products Found" for the trade name One A Day and for the company name Bayer on October 29, 2026. Neither brand was found in USP's verified products list, in the Informed Choice or Informed Sport searches, or in NSF Certified for Sport that day. A "not found on a date" result means only that; it says nothing about how either brand makes its tablets.

We also searched openFDA food enforcement reports for Centrum, One A Day, Haleon and Bayer on October 29, 2026, and all four searches returned no matches.

What a listing does mean is set by each program. NSF's page on supplement certification describes a label claim review, a toxicology review and a contaminant review under NSF/ANSI 173, plus annual audits. The NIH Office of Dietary Supplements states the limit plainly in its consumer guide to supplements: "These seals do not guarantee that a product is safe or effective." Our guide to running a registry check yourself walks through each database.

Price per tablet: the honest math

Price per tablet is the bottle price divided by the tablet count, and at one tablet a day, each cent per tablet adds $3.65 a year. Prices move, so this page does not print them. Check the current price on Amazon and the panel on the listing you actually buy.

What to look for when buying

• Match the name on the bottle. Healthy Advantage, Health Formula, Complete and Multi are all One A Day names for the same four lines; on Centrum, Silver marks the 50+ tablets.
• Read the iron row first. On these eight labels it runs from 0 mg (One A Day Men's) to 8 mg (Centrum Men and Centrum Silver Women 50+) to 18 mg (both women's tablets), and three 50+ tablets, both men's and One A Day Women's 50+, list no iron.
• Read the vitamin K row next. On One A Day it depends on the label version; on the four Centrum tablets we compared it reads 50 or 60 mcg.
• Check the count against the label. Our pins are tied to counts, such as 200 tablets for Centrum Silver Men 50+ and 100 for One A Day Men's 50+, and "packaging may vary" on a listing can mean either version arrives.
• Look up the trade name, not the logo. NSF lists Centrum by product name, so search the exact name printed on your bottle.
• Keep iron formulas away from small children. The iron-containing labels we read print: "Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6."

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FAQ

Who makes Centrum?
Haleon distributes Centrum: the 2025 label PDFs read "Distributed by: Haleon, Warren, NJ 07059". Older labels in the NIH database name Pfizer (2019 and 2020 copyrights) and GSK Consumer Healthcare (2021). Three 2025 PDFs, for Men, Silver Men 50+ and Silver Women 50+, print "Made in Canada", and NSF lists its Centrum products under Haleon US Holdings LLC.

Who makes One A Day?
Bayer. The One A Day retail labels in the NIH database read "Dist. by: Bayer HealthCare LLC, Whippany, NJ 07981" and state that Bayer, the Bayer Cross and One A Day are registered trademarks of Bayer. Two 2020 entries record a made in the USA line; we could not confirm a country line on the later labels.

Does One A Day Men's have iron?
No. The One A Day Men's Complete labels we read in the NIH database list iron at 0 mg (0%), the retail label entered in 2023 prints "Does Not Contain Iron", and the panel image on oneaday.com showed 0 mg on October 29, 2026. Centrum Men lists 8 mg (44% DV). Neither men's 50+ tablet lists an iron row.

What is the difference between Centrum and Centrum Silver?
Silver is Centrum's 50+ line. On the labels we read, Centrum Silver Adults 50+ lists no iron (Centrum Adults lists 18 mg), raises B12 from 6 mcg to 25 mcg, lists less selenium (19 mcg against 55 mcg) and adds 250 mcg lutein and 300 mcg lycopene. Silver Men 50+ goes further, with 100 mcg B12 and 300 mcg lutein.

Is Centrum in the NSF or USP registries?
On October 29, 2026, NSF's NSF/ANSI 173 listing showed 25 Centrum products under Haleon US Holdings LLC, including Centrum Men Multivitamin, Centrum Women Tablets, Centrum Silver Men 50+ and Centrum Silver Women 50+ Tablets. The Centrum Adults tablet was not found. Centrum was not found in USP's verified products list that day, and One A Day was not found in either.

Which is cheaper per tablet, Centrum or One A Day?
Prices move, so we do not print them. Divide the current price on Amazon by the tablet count, and compare bottles of the same count.

The bottom line

Centrum and One A Day share a format and the same 25 mcg of vitamin D on seven of the eight labels we pinned. What separates them on the label is iron, vitamin K, B12 and lutein.

Centrum Men lists 8 mg iron where One A Day Men's lists 0 mg. Centrum Silver lists 300 mcg lutein and 50 to 60 mcg vitamin K, where One A Day 50+ lists no lutein and 20 mcg or no K depending on the version. One A Day Men's 50+ lists 24 mg zinc and 117 mcg selenium against 15 mg and 21 mcg on Centrum Silver Men 50+.

Pick by the row that matters to you and by the bottle you can verify. If the Supplement Facts panel in your hand does not match any version in our tables, trust the panel, not this page. And if you take medication or have a medical condition, both labels already say what to do first: ask a health professional before use.

Sources and corrections

Label values come from the NIH database and from Haleon's label PDFs; registry results are what each database returned on the date shown.

• NIH Dietary Supplement Label Database, Centrum: 266189 Centrum Men (entered June 16, 2022), 257221 Centrum Women (December 18, 2021), 304930 Centrum Silver Men 50+ (January 24, 2024), 306026 Centrum Silver Women 50+ (January 24, 2024), 256971 Centrum Adults (November 19, 2021) and 304931 Centrum Silver Adults 50+ (November 22, 2023). Versions and values rechecked October 29, 2026.
• NIH Dietary Supplement Label Database, One A Day: 337439 and 269984 Men's Complete, 287759 and 270741 Women's Complete, 270560 and 266764 Men's 50+ Complete, 337448 and 270629 Women's 50+ Complete; rename UPCs from entries 2873, 178058, 240432, 17225, 178055 and 178201. Versions and values rechecked October 29, 2026.
• Haleon label PDFs for Centrum: Men, Women, Silver Men 50+, Silver Women 50+, Adults and Silver Adults 50+, files modified November 12 to 15, 2025, opened October 29, 2026.
• oneaday.com product pages and Supplement Facts images for Men's Multi, Women's Multi, Men's 50+ Multi and Women's 50+ Multi, viewed October 29, 2026.
• NSF/ANSI 173 listings for Centrum and One A Day, NSF Certified for Sport search, USP verified products list, and Informed Choice and Informed Sport searches, all October 29, 2026.
• NSF's supplement certification page and the NIH Office of Dietary Supplements consumer guide (updated January 4, 2023), opened October 29, 2026.
• 21 CFR 101.9, eCFR edition of October 1, 2026, for the DFE definition and the Daily Values.
• openFDA food enforcement reports, searches for Centrum, One A Day, Haleon and Bayer, October 29, 2026.

Published November 10, 2026. Label versions and registry listings checked October 29, 2026. Corrections will be listed here with their date.