Drug–Supplement Interactions

Licorice Root and Diuretics: What You Need to Know Licorice root supplements may seem harmless, but combining them with diuretics can trigger dangerous drops in potassium—known as hypokalemia—and other life-threatening imbalances. This guide explains the mechanisms behind this risk, how to recognize early warning signs, and best practices for using licorice safely, especially if you’re […]

Evening primrose oil (EPO), a supplement rich in gamma-linolenic acid (GLA), is popular for its anti-inflammatory and hormonal-balancing effects. But if you’re taking seizure medications, you may wonder: is EPO safe? Some medical sources warn it might lower the seizure threshold, while emerging evidence suggests otherwise. This guide explores the science behind EPO, seizure meds,

Can Saw Palmetto Increase Bleeding Risk with Blood Thinners? Saw palmetto (Serenoa repens) is widely used in herbal prostate supplements to relieve symptoms of benign prostatic hyperplasia (BPH). However, men taking anticoagulant medications like warfarin should be aware of a potential interaction: saw palmetto may increase the risk of bleeding. This guide breaks down the

Ashwagandha (Withania somnifera) is widely recognized for its calming properties, often used to alleviate stress and promote sleep. However, when combined with sedative medications, it may amplify drowsiness and other side effects. This guide explores the potential risks of combining ashwagandha with sedatives, safe dosage ranges, optimal timing for use, and essential precautions to ensure

Understanding the Risks of CBD and Warfarin Combined As cannabidiol (CBD) use grows in popularity, patients on anticoagulant therapy—particularly warfarin—face important safety considerations. The potential for a serious CBD warfarin interaction stems from how CBD affects liver enzymes critical for drug metabolism. Specifically, CBD can inhibit CYP450 enzymes such as CYP2C9, which metabolizes warfarin’s most

Can NAC Amplify Nitroglycerin’s Effects on Blood Pressure? Summary: The NAC nitroglycerin interaction offers powerful therapeutic potential in cardiovascular care, especially for angina and acute coronary syndromes. However, this vasodilation synergy demands precise dosing and safety monitoring. Understanding the NAC and Nitroglycerin Synergy How Nitroglycerin Works Nitroglycerin (glyceryl trinitrate) is a long-standing treatment for angina

If you or a loved one is managing Parkinson’s disease, understanding the interaction between vitamin B6 and levodopa is crucial. While levodopa is a cornerstone of Parkinson’s treatment, certain supplements—particularly pyridoxine (vitamin B6)—can interfere with its effectiveness. This guide explores how this interference happens, the risks of deficiency, and expert-backed strategies for safe supplementation. You’ll

Antibiotics can disrupt your gut microbiome—but taking probiotics at the right time can help maintain balance and prevent digestive issues. This guide explores the best timing for probiotics with antibiotics, which strains are most effective, and how long to continue them for optimal gut flora management. Quick Summary: Best Timing for Probiotics with Antibiotics Factor

Combining ginkgo biloba, a popular herbal supplement, with aspirin has sparked ongoing debate about safety. Both substances affect blood clotting, and when taken together, may heighten bleeding risks. This guide explores the latest evidence on ginkgo aspirin bleeding risk, highlights potential side effects, and offers practical recommendations for safer use. Quick Summary: Is It Safe

Why You Should Be Concerned About Potassium and ACE Inhibitors ACE inhibitors are cornerstone medications for conditions like high blood pressure, heart failure, and chronic kidney disease. But their interaction with potassium—especially through supplements or high-potassium foods—can be dangerous. This guide breaks down the key facts about the potassium ACE inhibitor interaction, outlines signs of