The old theory that high-dose vitamin C raises ethinylestradiol has been largely debunked. What current evidence says about vitamin C and the pill.
Does Vitamin C Affect Birth Control Effectiveness? Read More »
SAM-e is a popular mood supplement, but combined with an SSRI it can push serotonin too high. The serotonin syndrome risk, the adjunct studies, and the caution.
Can You Take SAM-e With SSRIs Like Sertraline? Read More »
L-tryptophan plus an SSRI can raise serotonin too far and trigger serotonin syndrome. How it differs from 5-HTP, the real risk, and safer sleep options.
Is L-Tryptophan Safe With SSRIs? The Serotonin Syndrome Risk Read More »
SSRIs don’t classically deplete B vitamins, but low folate, B12 and B6 are linked to poorer antidepressant response. What the evidence supports supplementing.
Do SSRIs Like Sertraline Deplete B Vitamins (B6, Folate, B12)? Read More »
Ashwagandha is often taken with SSRIs like sertraline, but there are real cautions: additive sedation, thyroid effects, and rare liver injury. The evidence.
Is Ashwagandha Safe With Sertraline (Zoloft) and Other SSRIs? Read More »
Cymbalta and Effexor raise serotonin, so St. John’s wort, 5-HTP, SAM-e and tryptophan can trigger serotonin syndrome. The full avoid list for SNRIs.
Supplements to Avoid With Cymbalta and Effexor (SNRIs) Read More »
Grapefruit raises blood levels of some antidepressants like sertraline and buspirone via CYP3A4. Which ones matter, which don’t, and how long to wait.
Grapefruit and Antidepressants: Sertraline, Buspirone and the SSRIs Read More »
Doxycycline binds to calcium, iron, magnesium and zinc, which can wipe out the antibiotic’s absorption. Exactly how long to wait and what’s safe.
Supplements to Avoid With Doxycycline: Calcium, Iron, Magnesium and Dairy Timing Read More »
Bone and heart shoppers add vitamin K2 MK-7 not realizing even microgram doses can blunt warfarin and drop your INR. The evidence and the safer options.
Vitamin K2 (MK-7) and Warfarin: Why Even Small Doses Matter Read More »
Normal vitamin C is fine with warfarin, but high-dose (over 1,000 mg) has case reports of warfarin resistance and lower INR. The evidence and a safe ceiling.
Vitamin C and Warfarin: Does High-Dose Vitamin C Affect INR? Read More »
